Stroke Recovery Animal Models & CRO Services

Stroke affects people of all ages. There are approximately 5 million stroke survivors in the U.S. Stroke commonly results in substantial and multi-dimensional disability in patients, including disturbances in walking, speech, arm function, balance, memory, vision, swallowing, etc.

Some degree of recovery is common after stroke. However, other than physical, occupational, and speech therapies, there are no drugs, devices, or cell therapies currently on the market that accelerate or enhance recovery after stroke.

Biotrofix investigators were among the pioneers in the development of animal models of stroke recovery. These include rat models of focal stroke, compatible with long survival of animals, suitable for investigation of recovery-promoting treatments. Such treatments are typically administered days after stroke onset. Endpoints for these studies include serial behavioral evaluation of animals and histology.

Download STROKE RECOVERY MODEL (.pdf)