Intracerebral Hemorrhage Models & CRO Services

About 15% of the estimated 800,000 strokes occurring in the U.S. every year represent intracerebral hemorrhage. Spontaneous bleeding into the brain occurs due to longstanding hypertension, cerebral amyloid angiopathy (CAA), or ruptured intracranial aneurysm. Clinical outcome may be devastating, including patient death.

Biotrofix has developed a quantifiable and reproducible model of intracerebral hemorrhage (ICH) in rodents. This model is useful for testing the effects of anticoagulant and procoagulant drugs, as well as treatments that reduce the secondary consequences (swelling, mass effect, etc.) that accompany ICH."

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Biotrofix is a premier preclinical contract research organization specializing in animal models of CNS, cardiac and vascular disease. With years of experience, both academic, commercial, clients throughout the biotech and pharmaceutical industries, Biotrofix delivers industry-leading preclinical CRO services, including rodent models of acute stroke and stroke recovery, preclinical CRO services for Alzheimer's Disease, transgenic animal models for ALS, as well as CRO services for brain injury, preclinical CRO services for spinal cord injury and related cardiac drug discovery and development.